Editorials:

Thomas M. Annesley, James C. Boyd, and Nader Rifai

Publication Ethics: Clinical Chemistry Editorial Standards
Clin Chem 2009 55: 1-4. Published online November 21, 2008; 10.1373/clinchem.2008.120055 [Extract] [Full Text] [PDF]  

David A. Morrow and Elliott M. Antman

Evaluation of High-Sensitivity Assays for Cardiac Troponin
Clin Chem 2009 55: 5-8. Published online November 21, 2008; 10.1373/clinchem.2008.117218 [Extract] [Full Text] [PDF]  

Bertil Lindahl

Multimarker Approach for Diagnosis of Acute Myocardial Infarction: Better Answers Need Better Questions
Clin Chem 2009 55: 9-11. Published online November 21, 2008; 10.1373/clinchem.2008.117572 [Extract] [Full Text] [PDF]  

Alan H.B. Wu

Novel Biomarkers of Cardiovascular Disease: Myeloperoxidase for Acute and/or Chronic Heart Failure?
Clin Chem 2009 55: 12-14. Published online November 21, 2008; 10.1373/clinchem.2008.118208 [Extract] [Full Text] [PDF]  

Andrew J. Vickers and Hans Lilja

Cutpoints in Clinical Chemistry: Time for Fundamental Reassessment
Clin Chem 2009 55: 15-17. Published online November 21, 2008; 10.1373/clinchem.2008.114694 [Extract] [Full Text] [PDF]  

Perspectives:

Mitchell G. Scott, David E. Bruns, James C. Boyd, and David B. Sacks

Tight Glucose Control in the Intensive Care Unit: Are Glucose Meters up to the Task?
Clin Chem 2009 55: 18-20. Published online November 21, 2008; 10.1373/clinchem.2008.117291 [Extract] [Full Text] [PDF]  

Joseph P. McConnell and Allan S. Jaffe

The Spin Stops Here: Inhibition of Lipoprotein-Associated Phospholipase A2— A Promising Target but a Negative Initial Trial?
Clin Chem 2009 55: 21-23. Published online December 1, 2008; 10.1373/clinchem.2008.118364 [Extract] [Full Text] [PDF]  

Reviews:

W. Greg Miller, David E. Bruns, Glen L. Hortin, Sverre Sandberg, Kristin M. Aakre, Matthew J. McQueen, Yoshihisa Itoh, John C. Lieske, David W. Seccombe, Graham Jones, David M. Bunk, Gary C. Curhan, Andrew S. Narva on behalf of the National Kidney Disease Education Program-IFCC Working Group on Standardization of Albumin in Urine

Current Issues in Measurement and Reporting of Urinary Albumin Excretion
Clin Chem 2009 55: 24-38. Published online November 21, 2008; 10.1373/clinchem.2008.106567 [Abstract] [Full Text] [PDF] Supplemental Data  

Daniel I. Chasman, Guillaume Paré, and Paul M Ridker

Population-Based Genomewide Genetic Analysis of Common Clinical Chemistry Analytes
Clin Chem 2009 55: 39-51. Published online November 21, 2008; 10.1373/clinchem.2008.107243 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Alan H.B. Wu, Quynh Anh Lu, John Todd, Joachim Moecks, and Frank Wians

Short- and Long-Term Biological Variation in Cardiac Troponin I Measured with a High-Sensitivity Assay: Implications for Clinical Practice
Clin Chem 2009 55: 52-58. Published online November 6, 2008; 10.1373/clinchem.2008.107391 [Abstract] [Full Text] [PDF]  

Keyur B. Shah, Willem J. Kop, Robert H. Christenson, Deborah B. Diercks, Dick Kuo, Sue Henderson, Karen Hanson, Mandeep R. Mehra, and Christopher R. deFilippi

Lack of Diagnostic and Prognostic Utility of Circulating Plasma Myeloperoxidase Concentrations in Patients Presenting with Dyspnea
Clin Chem 2009 55: 59-67. Published online November 6, 2008; 10.1373/clinchem.2008.108159 [Abstract] [Full Text] [PDF] Supplemental Data  

Thomas Mueller, Benjamin Dieplinger, Werner Poelz, Georg Endler, Oswald F. Wagner, and Meinhard Haltmayer

Amino-Terminal Pro–B-Type Natriuretic Peptide as Predictor of Mortality in Patients with Symptomatic Peripheral Arterial Disease: 5-Year Follow-Up Data from the Linz Peripheral Arterial Disease Study
Clin Chem 2009 55: 68-77. Published online November 6, 2008; 10.1373/clinchem.2008.108753 [Abstract] [Full Text] [PDF]  

Wayne L. Miller, Karen A. Hartman, Diane E. Grill, John C. Burnett, Jr, and Allan S. Jaffe

Only Large Reductions in Concentrations of Natriuretic Peptides (BNP and NT-proBNP) Are Associated with Improved Outcome in Ambulatory Patients with Chronic Heart Failure
Clin Chem 2009 55: 78-84. Published online November 21, 2008; 10.1373/clinchem.2008.108928 [Abstract] [Full Text] [PDF] Supplemental Data  

Kai M. Eggers, Allan S. Jaffe, Lars Lind, Per Venge, and Bertil Lindahl

Value of Cardiac Troponin I Cutoff Concentrations below the 99th Percentile for Clinical Decision-Making
Clin Chem 2009 55: 85-92. Published online November 6, 2008; 10.1373/clinchem.2007.101683 [Abstract] [Full Text] [PDF] Supplemental Data  

Fred S. Apple, Stephen W. Smith, Lesly A. Pearce, and MaryAnn M. Murakami

Assessment of the Multiple-Biomarker Approach for Diagnosis of Myocardial Infarction in Patients Presenting with Symptoms Suggestive of Acute Coronary Syndrome
Clin Chem 2009 55: 93-100. Published online November 21, 2008; 10.1373/clinchem.2008.102905 [Abstract] [Full Text] [PDF]  

Alma Mingels, Leo Jacobs, Etienne Michielsen, Joost Swaanenburg, Will Wodzig, and Marja van Dieijen-Visser

Reference Population and Marathon Runner Sera Assessed by Highly Sensitive Cardiac Troponin T and Commercial Cardiac Troponin T and I Assays
Clin Chem 2009 55: 101-108. Published online November 6, 2008; 10.1373/clinchem.2008.106427 [Abstract] [Full Text] [PDF] Supplemental Data  

Per Venge, Stefan James, Leif Jansson, and Bertil Lindahl

Clinical Performance of Two Highly Sensitive Cardiac Troponin I Assays
Clin Chem 2009 55: 109-116. Published online November 6, 2008; 10.1373/clinchem.2008.106500 [Abstract] [Full Text] [PDF]  

Crina I. Balog, Paul J. Hensbergen, Rico Derks, Jaco J. Verweij, Govert J. van Dam, Birgitte J. Vennervald, André M. Deelder, and Oleg A. Mayboroda

Novel Automated Biomarker Discovery Work Flow for Urinary Peptidomics
Clin Chem 2009 55: 117-125. Published online November 6, 2008; 10.1373/clinchem.2008.108795 [Abstract] [Full Text] [PDF] Supplemental Data  

Drug Monitoring and Toxicology:

Julia C. Drees, Judy A. Stone, Kent R. Olson, Kathryn H. Meier, Alan M. Gelb, and Alan H. B. Wu

Clinical Utility of an LC-MS/MS Seizure Panel for Common Drugs Involved in Drug-Induced Seizures
Clin Chem 2009 55: 126-133. Published online November 21, 2008; 10.1373/clinchem.2008.110858 [Abstract] [Full Text] [PDF] Supplemental Data  

Molecular Diagnostics and Genetics:

Stefan Greisenegger, Sonja Zehetmayer, Peter Bauer, Georg Endler, Julia Ferrari, Wilfried Lang, Michael Janisiw, Lori Steiner, Suzanne Cheng, Wolfgang Lalouschek, and Christine Mannhalter

Polymorphisms in Inflammatory Genes and the Risk of Ischemic Stroke and Transient Ischemic Attack: Results of a Multilocus Genotyping Assay
Clin Chem 2009 55: 134-138. Published online November 21, 2008; 10.1373/clinchem.2008.112151 [Abstract] [Full Text] [PDF] Supplemental Data  

Klaus Meyer, Åse Fredriksen, and Per Magne Ueland

MALDI-TOF MS Genotyping of Polymorphisms Related to 1-Carbon Metabolism Using Common and Mass-Modified Terminators
Clin Chem 2009 55: 139-149. Published online November 6, 2008; 10.1373/clinchem.2008.115378 [Abstract] [Full Text] [PDF] Supplemental Data  

Pediatric Clinical Chemistry:

Daniela Basso, Graziella Guariso, Paola Fogar, Alessandra Meneghel, Carlo-Federico Zambon, Filippo Navaglia, Eliana Greco, Stefania Schiavon, Massimo Rugge, and Mario Plebani

Antibodies against Synthetic Deamidated Gliadin Peptides for Celiac Disease Diagnosis and Follow-Up in Children
Clin Chem 2009 55: 150-157. Published online November 6, 2008; 10.1373/clinchem.2008.110395 [Abstract] [Full Text] [PDF] Supplemental Data  

Victor R. De Jesus, X. Kate Zhang, Joan Keutzer, Olaf A. Bodamer, Adolf Mühl, Joseph J. Orsini, Michele Caggana, Robert F. Vogt, and W. Harry Hannon

Development and Evaluation of Quality Control Dried Blood Spot Materials in Newborn Screening for Lysosomal Storage Disorders
Clin Chem 2009 55: 158-164. Published online November 6, 2008; 10.1373/clinchem.2008.111864 [Abstract] [Full Text] [PDF] Supplemental Data  

Brief Communications:

Katharine M. McGreevy, Stuart R. Lipsitz, Jeffrey A. Linder, Eric Rimm, and David G. Hoel

Using Median Regression to Obtain Adjusted Estimates of Central Tendency for Skewed Laboratory and Epidemiologic Data
Clin Chem 2009 55: 165-169. Published online November 21, 2008; 10.1373/clinchem.2008.106260 [Abstract] [Full Text] [PDF] Supplemental Data  

Laure Elens, Sophie Veriter, Vincent Di Fazio, Roger Vanbinst, Daniel Boesmans, Pierre Wallemacq, and Vincent Haufroid

Quantification of 8 HIV-Protease Inhibitors and 2 Nonnucleoside Reverse Transcriptase Inhibitors by Ultra-Performance Liquid Chromatography with Diode Array Detection
Clin Chem 2009 55: 170-174. Published online November 21, 2008; 10.1373/clinchem.2008.108647 [Abstract] [Full Text] [PDF] Supplemental Data  

Michaela Plaikner, Andreas Peer, Gerda Falkensammer, Christoph Schmidauer, Christoph Pechlaner, Andrea Griesmacher, Otmar Pachinger, and Johannes Mair

Lack of Association of Soluble CD40 Ligand with the Presence of Acute Myocardial Infarction or Ischemic Stroke in the Emergency Department
Clin Chem 2009 55: 175-178. Published online December 1, 2008; 10.1373/clinchem.2008.114231 [Abstract] [Full Text] [PDF] Supplemental Data  

Xiaohu Xia, Ye Xu, Xilin Zhao, and Qingge Li

Lateral Flow Immunoassay Using Europium Chelate-Loaded Silica Nanoparticles as Labels
Clin Chem 2009 55: 179-182. Published online October 30, 2008; 10.1373/clinchem.2008.114561 [Abstract] [Full Text] [PDF] Supplemental Data  

Catherine Massart, Rémy Sapin, Jacqueline Gibassier, Arnaud Agin, and Michèle d'Herbomez

Intermethod Variability in TSH-Receptor Antibody Measurement: Implication for the Diagnosis of Graves Disease and for the Follow-Up of Graves Ophthalmopathy
Clin Chem 2009 55: 183-186. Published online November 21, 2008; 10.1373/clinchem.2008.115162 [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Case Study:

Kevin F. Foley, Marina G. Silveira, Jean M. Hornseth, Keith D. Lindor, and Joseph P. McConnell

A Patient with Primary Biliary Cirrhosis and Elevated LDL Cholesterol
Clin Chem 2009 55: 187-192. [Extract] [Full Text] [PDF]  

James Otvos

Commentary
Clin Chem 2009 55: 191-192. [Extract] [Full Text] [PDF]  

Citation Classics:

Toshiharu Nagatsu

Simple Photometric Assay of Dopamine-β-Hydroxylase Activity in Human Blood: Useful in Clinical Chemistry
Clin Chem 2009 55: 193-194. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Angelo Cacchio, Elisabetta De Blasis, Francesco Rosa, Domenico De Blasis, Fosco de Paulis, Valter Santilli, and Vittorio Calvisi

Response of Bone Turnover Biochemical Markers to Extracorporeal Shock Wave Therapy in the Management of Long-Bone Nonunions
Clin Chem 2009 55: 195-196. [Extract] [Full Text] [PDF]  

Alan H.B. Wu, Sara J. Agee, Quynh Anh Lu, John Todd, and Allan S. Jaffe

Specificity of a High-Sensitivity Cardiac Troponin I Assay Using Single-Molecule–Counting Technology
Clin Chem 2009 55: 196-198. [Extract] [Full Text] [PDF]  

Clinical Chemist:

Lily Robinson and the Art of Secret Poisoning
Clin Chem 2009 55: 199-200. [Extract] [Full Text] [PDF]  

Overseas Laboratory Medicine
Clin Chem 2009 55: 200. [Extract] [Full Text] [PDF]  

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