Introduction:

Ian Young and Nader Rifai

High-Sensitivity C-Reactive Protein and Cardiovascular Disease
Clin Chem 2009 55: 201-202. Published online December 18, 2008; 10.1373/clinchem.2008.120527 [Extract] [Full Text] [PDF]  

Editorials:

Paul O. Collinson

Concentrations of C-Reactive Protein and B-Type Natriuretic Peptide 30 Days after Acute Coronary Syndromes Independently Predict Hospitalization for Heart Failure and Cardiovascular Death: Just Another Brick in the Wall?
Clin Chem 2009 55: 203-205. Published online December 18, 2008; 10.1373/clinchem.2008.119198 [Extract] [Full Text] [PDF]  

Ishwarlal Jialal, Subodh Verma, and Sridevi Devaraj

Inhibition of Endothelial Nitric Oxide Synthase by C-Reactive Protein: Clinical Relevance
Clin Chem 2009 55: 206-208. Published online December 18, 2008; 10.1373/clinchem.2008.119206 [Extract] [Full Text] [PDF]  

Reflection:

Paul M Ridker

C-Reactive Protein: Eighty Years from Discovery to Emergence as a Major Risk Marker for Cardiovascular Disease
Clin Chem 2009 55: 209-215. Published online December 18, 2008; 10.1373/clinchem.2008.119214 [Extract] [Full Text] [PDF]  

Perspective:

Wolfgang Koenig

Is hsCRP Back on Board? Implications from the JUPITER Trial
Clin Chem 2009 55: 216-218. Published online December 12, 2008; 10.1373/clinchem.2008.115915 [Extract] [Full Text] [PDF]  

Mini-Review:

Samia Mora, Kiran Musunuru, and Roger S. Blumenthal

The Clinical Utility of High-Sensitivity C-Reactive Protein in Cardiovascular Disease and the Potential Implication of JUPITER on Current Practice Guidelines
Clin Chem 2009 55: 219-228. Published online December 18, 2008; 10.1373/clinchem.2008.109728 [Abstract] [Full Text] [PDF] Supplemental Data  

Reviews:

Sridevi Devaraj, Uma Singh, and Ishwarlal Jialal

The Evolving Role of C-Reactive Protein in Atherothrombosis
Clin Chem 2009 55: 229-238. Published online December 18, 2008; 10.1373/clinchem.2008.108886 [Abstract] [Full Text] [PDF]  

Aroon D. Hingorani, Tina Shah, Juan P. Casas, Steve E. Humphries, and Philippa J. Talmud

C-Reactive Protein and Coronary Heart Disease: Predictive Test or Therapeutic Target?
Clin Chem 2009 55: 239-255. Published online December 29, 2008; 10.1373/clinchem.2008.115923 [Abstract] [Full Text] [PDF] Supplemental Data  

Jian Shen and Jose M. Ordovas

Impact of Genetic and Environmental Factors on hsCRP Concentrations and Response to Therapeutic Agents
Clin Chem 2009 55: 256-264. Published online December 12, 2008; 10.1373/clinchem.2008.117754 [Abstract] [Full Text] [PDF] Supplemental Data  

Proteomics and Protein Markers:

Benjamin M. Scirica, Christopher P. Cannon, Marc S. Sabatine, Petr Jarolim, Sarah Sloane, Nader Rifai, Eugene Braunwald, David A. Morrow for the PROVE IT–TIMI 22 Investigators

Concentrations of C-Reactive Protein and B-Type Natriuretic Peptide 30 Days after Acute Coronary Syndromes Independently Predict Hospitalization for Heart Failure and Cardiovascular Death
Clin Chem 2009 55: 265-273. Published online December 12, 2008; 10.1373/clinchem.2008.117192 [Abstract] [Full Text] [PDF]  

Hongjing Guan, Peihua Wang, Rutai Hui, Matthew L. Edin, Darryl C. Zeldin, and Dao Wen Wang

Adeno-Associated Virus–Mediated Human C-Reactive Protein Gene Delivery Causes Endothelial Dysfunction and Hypertension in Rats
Clin Chem 2009 55: 274-284. Published online December 4, 2008; 10.1373/clinchem.2008.115857 [Abstract] [Full Text] [PDF] Supplemental Data  

Yoshiko Fujita, Akemi Kakino, Norihisa Nishimichi, Saburo Yamaguchi, Yuko Sato, Sachiko Machida, Luciano Cominacini, Yves Delneste, Haruo Matsuda, and Tatsuya Sawamura

Oxidized LDL Receptor LOX-1 Binds to C-Reactive Protein and Mediates Its Vascular Effects
Clin Chem 2009 55: 285-294. Published online December 12, 2008; 10.1373/clinchem.2008.119750 [Abstract] [Full Text] [PDF]  

Tanja Vollmer, Cornelia Piper, Knut Kleesiek, and Jens Dreier

Lipopolysaccharide-Binding Protein: A New Biomarker for Infectious Endocarditis?
Clin Chem 2009 55: 295-304. Published online October 2, 2008; 10.1373/clinchem.2008.106195 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Robert J. Glynn, Jean G. MacFadyen, and Paul M Ridker

Tracking of High-Sensitivity C-Reactive Protein after an Initially Elevated Concentration: The JUPITER Study
Clin Chem 2009 55: 305-312. Published online December 18, 2008; 10.1373/clinchem.2008.120642 [Abstract] [Full Text] [PDF]  

David E. Chiriboga, Yunsheng Ma, Wenjun Li, Edward J. Stanek, III, James R. Hébert, Philip A. Merriam, Eric S. Rawson, and Ira S. Ockene

Seasonal and Sex Variation of High-Sensitivity C-Reactive Protein in Healthy Adults: A Longitudinal Study
Clin Chem 2009 55: 313-321. [Abstract] [Full Text] [PDF]  

Regina Rückerl, Annette Peters, Natalie Khuseyinova, Mariarita Andreani, Wolfgang Koenig, Christa Meisinger, Konstantina Dimakopoulou, Jordi Sunyer, Timo Lanki, Fredrik Nyberg, and Alexandra Schneider

Determinants of the Acute-Phase Protein C-Reactive Protein in Myocardial Infarction Survivors: The Role of Comorbidities and Environmental Factors
Clin Chem 2009 55: 322-335. Published online December 18, 2008; 10.1373/clinchem.2008.112334 [Abstract] [Full Text] [PDF] Supplemental Data  

Tomer Shemesh, Kevin G. Rowley, Alicia J. Jenkins, James D. Best, and Kerin O'Dea

C-Reactive Protein Concentrations Are Very High and More Stable over Time Than the Traditional Vascular Risk Factors Total Cholesterol and Systolic Blood Pressure in an Australian Aboriginal Cohort
Clin Chem 2009 55: 336-341. Published online December 12, 2008; 10.1373/clinchem.2008.115360 [Abstract] [Full Text] [PDF]  

Mary M. Kimberly, Samuel P. Caudill, Hubert W. Vesper, Elizabeth A. Monsell, W. Greg Miller, Robert Rej, Nader Rifai, Francesco Dati, and Gary L. Myers

Standardization of High-Sensitivity Immunoassays for Measurement of C-Reactive Protein; II: Two Approaches for Assessing Commutability of a Reference Material
Clin Chem 2009 55: 342-350. Published online December 12, 2008; 10.1373/clinchem.2008.115907 [Abstract] [Full Text] [PDF] Supplemental Data  

Cathy C. Lee, Nai-chieh Yuko You, Yiqing Song, Yi-Hsiang Hsu, JoAnn Manson, Lauren Nathan, Lesley Tinker, and Simin Liu

Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with Its Plasma Protein Concentrations: Findings from the Women’s Health Initiative Observational Cohort
Clin Chem 2009 55: 351-360. Published online December 18, 2008; 10.1373/clinchem.2008.117176 [Abstract] [Full Text] [PDF] Supplemental Data  

Brief Communications:

Uma Singh, Sridevi Devaraj, and Ishwarlal Jialal

C-Reactive Protein Stimulates Myeloperoxidase Release from Polymorphonuclear Cells and Monocytes: Implications for Acute Coronary Syndromes
Clin Chem 2009 55: 361-364. Published online December 12, 2008; 10.1373/clinchem.2008.109207 [Abstract] [Full Text] [PDF]  

Luigi M. Biasucci, Giovanna Liuzzo, Roberta Della Bona, Milena Leo, Gina Biasillo, Dominick J. Angiolillo, Antonio Abbate, Vittoria Rizzello, Giampaolo Niccoli, Simona Giubilato, and Filippo Crea

Different Apparent Prognostic Value of hsCRP in Type 2 Diabetic and Nondiabetic Patients with Acute Coronary Syndromes
Clin Chem 2009 55: 365-368. [Abstract] [Full Text] [PDF]  

Clinical Case Study:

Paul M Ridker

Myocardial Infarction in a 72-Year-Old Woman with Low LDL-C and Increased hsCRP: Implications for Statin Therapy
Clin Chem 2009 55: 369-374. [Extract] [Full Text] [PDF]  

Ernst J. Schaefer

Commentary
Clin Chem 2009 55: 374-375. [Extract] [Full Text] [PDF]  

Eric Yang and Christie M. Ballantyne

Commentary
Clin Chem 2009 55: 375. [Extract] [Full Text] [PDF]  

Citation Classics:

Russell P. Tracy

Simple and Reproducible ELISA for C-Reactive Protein
Clin Chem 2009 55: 376-377. [Extract] [Full Text] [PDF]  

Preamble:

NACB LMPG Committee Members, Gary L. Myers, Robert H.M. Christenson, Mary Cushman, Christie M. Ballantyne, Gerald R. Cooper, Christine M. Pfeiffer, Scott M. Grundy, Darwin R. Labarthe, Daniel Levy, Nader Rifai, and Peter W.F. Wilson

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Emerging Biomarkers for Primary Prevention of Cardiovascular Disease
Clin Chem 2009 55: 378-384. Published online December 23, 2008; 10.1373/clinchem.2008.115899 [Abstract] [Full Text] [PDF]  

Clinical Chemist:

Lily Robinson and the Art of Secret Poisoning: Recollections
Clin Chem 2009 55: 385. [Extract] [Full Text] [PDF]  

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