Editorials:

Ulf-Håkan Stenman

Detection of Illicit Use of Growth Hormone
Clin Chem 2009 55: 387-388. Published online January 15, 2009; 10.1373/clinchem.2008.119263 [Extract] [Full Text] [PDF]  

Thomas A. Fleisher and Joao B. Oliveira

Functional Flow Cytometry Testing: An Emerging Approach for the Evaluation of Genetic Disease
Clin Chem 2009 55: 389-390. Published online January 15, 2009; 10.1373/clinchem.2008.119248 [Extract] [Full Text] [PDF]  

Allan Sniderman and Amirreza Solhpour

Targeting Targets for LDL-Lowering Therapy: Lessons from the Collaborative Atorvastatin Diabetes Study (CARDS)
Clin Chem 2009 55: 391-393. Published online January 15, 2009; 10.1373/clinchem.2009.119255 [Extract] [Full Text] [PDF]  

Johannes Mair

Clinical Significance of Pro-B-Type Natriuretic Peptide Glycosylation and Processing
Clin Chem 2009 55: 394-397. Published online January 15, 2009; 10.1373/clinchem.2008.119271 [Extract] [Full Text] [PDF]  

T. Keith Brock, Nicole L. Gentile, Richard F. Louie, Nam K. Tran, Tyler Kitano, and Gerald J. Kost

Assessing Thrombin Generation at the Point of Care
Clin Chem 2009 55: 398-399. Published online January 23, 2009; 10.1373/clinchem.2008.122747 [Extract] [Full Text] [PDF]  

Perspectives:

William E. Harmon

Glomerular Filtration Rate in Children with Chronic Kidney Disease
Clin Chem 2009 55: 400-401. Published online January 23, 2009; 10.1373/clinchem.2008.123067 [Extract] [Full Text] [PDF]  

W. Greg Miller

Estimating Equations for Glomerular Filtration Rate in Children: Laboratory Considerations
Clin Chem 2009 55: 402-403. Published online January 23, 2009; 10.1373/clinchem.2008.122218 [Extract] [Full Text] [PDF]  

Robert E. Gerszten, Marc Sabatine, and Thomas J. Wang

New Antibody Assays for Cardiovascular Disease: Future Tools for the Clinical Chemist?
Clin Chem 2009 55: 404-406. Published online January 23, 2009; 10.1373/clinchem.2008.118646 [Extract] [Full Text] [PDF]  

Special Reports:

John H. Contois, Joseph P. McConnell, Amar A. Sethi, Gyorgy Csako, Sridevi Devaraj, Daniel M. Hoefner, and G. Russell Warnick

Apolipoprotein B and Cardiovascular Disease Risk: Position Statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices
Clin Chem 2009 55: 407-419. Published online January 23, 2009; 10.1373/clinchem.2008.118356 [Abstract] [Full Text] [PDF] Supplemental Data  

Mini-Review:

Bernard Goichot, Rémy Sapin, and Jean Louis Schlienger

Subclinical Hyperthyroidism: Considerations in Defining the Lower Limit of the Thyrotropin Reference Interval
Clin Chem 2009 55: 420-424. Published online January 15, 2009; 10.1373/clinchem.2008.110627 [Abstract] [Full Text] [PDF]  

Review:

Javier A. Menendez, Alejandro Vazquez-Martin, Francisco Jose Ortega, and Jose Manuel Fernandez-Real

Fatty Acid Synthase: Association with Insulin Resistance, Type 2 Diabetes, and Cancer
Clin Chem 2009 55: 425-438. Published online January 30, 2009; 10.1373/clinchem.2008.115352 [Abstract] [Full Text] [PDF] Supplemental Data  

Point/Counterpoint:

John E.M. Midgley and Nic D. Christofides

Point: Legitimate and Illegitimate Tests of Free-Analyte Assay Function
Clin Chem 2009 55: 439-441. Published online January 15, 2009; 10.1373/clinchem.2008.116525 [Extract] [Full Text] [PDF]  

R. Bruce Wilcox and Jerald C. Nelson

Counterpoint: Legitimate and Illegitimate Tests of Free-Analyte Assay Function: We Need to Identify the Factors That Influence Free-Analyte Assay Results
Clin Chem 2009 55: 442-444. Published online January 23, 2009; 10.1373/clinchem.2008.120154 [Extract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Martin Bidlingmaier, Jennifer Suhr, Andrea Ernst, Zida Wu, Alexandra Keller, Christian J. Strasburger, and Andreas Bergmann

High-Sensitivity Chemiluminescence Immunoassays for Detection of Growth Hormone Doping in Sports
Clin Chem 2009 55: 445-453. Published online January 23, 2009; 10.1373/clinchem.2008.112458 [Abstract] [Full Text] [PDF] Supplemental Data  

Allan J. Barnes, Bruno S. De Martinis, David A. Gorelick, Robert S. Goodwin, Erin A. Kolbrich, and Marilyn A. Huestis

Disposition of MDMA and Metabolites in Human Sweat Following Controlled MDMA Administration
Clin Chem 2009 55: 454-462. Published online January 23, 2009; 10.1373/clinchem.2008.117093 [Abstract] [Full Text] [PDF]  

Cancer Diagnostics:

Shareef A. Nahas, Anthony W. Butch, Liutao Du, and Richard A. Gatti

Rapid Flow Cytometry–Based Structural Maintenance of Chromosomes 1 (SMC1) Phosphorylation Assay for Identification of Ataxia-Telangiectasia Homozygotes and Heterozygotes
Clin Chem 2009 55: 463-472. Published online January 15, 2009; 10.1373/clinchem.2008.107128 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Valentine Charlton-Menys, D. John Betteridge, Helen Colhoun, John Fuller, Michael France, Graham A. Hitman, Shona J. Livingstone, H. Andrew W. Neil, Connie B. Newman, Michael Szarek, David A. DeMicco, and Paul N. Durrington

Targets of Statin Therapy: LDL Cholesterol, Non-HDL Cholesterol, and Apolipoprotein B in Type 2 Diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS)
Clin Chem 2009 55: 473-480. Published online January 15, 2009; 10.1373/clinchem.2008.111401 [Abstract] [Full Text] [PDF] Supplemental Data  

Michael Y. Tsai, Na Li, A. Richey Sharrett, Steven Shea, David R. Jacobs, Jr, Russell Tracy, Donna Arnett, Valerie Arends, and Wendy Post

Associations of Genetic Variants in ATP-Binding Cassette A1 and Cholesteryl Ester Transfer Protein and Differences in Lipoprotein Subclasses in the Multi-Ethnic Study of Atherosclerosis
Clin Chem 2009 55: 481-488. Published online January 8, 2009; 10.1373/clinchem.2008.107995 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Alexander G. Semenov, Alexander B. Postnikov, Natalia N. Tamm, Karina R. Seferian, Natalia S. Karpova, Marina N. Bloshchitsyna, Ekaterina V. Koshkina, Mihail I. Krasnoselsky, Daria V. Serebryanaya, and Alexey G. Katrukha

Processing of Pro–Brain Natriuretic Peptide Is Suppressed by O-Glycosylation in the Region Close to the Cleavage Site
Clin Chem 2009 55: 489-498. Published online January 23, 2009; 10.1373/clinchem.2008.113373 [Abstract] [Full Text] [PDF] Supplemental Data  

Giovanni Palladini, Paola Russo, Tiziana Bosoni, Laura Verga, Gabriele Sarais, Francesca Lavatelli, Mario Nuvolone, Laura Obici, Simona Casarini, Simona Donadei, Riccardo Albertini, Gabriella Righetti, Maddalena Marini, Maria Stella Graziani, Gian Vico Melzi D'Eril, Remigio Moratti, and Giampaolo Merlini

Identification of Amyloidogenic Light Chains Requires the Combination of Serum-Free Light Chain Assay with Immunofixation of Serum and Urine
Clin Chem 2009 55: 499-504. Published online January 8, 2009; 10.1373/clinchem.2008.117143 [Abstract] [Full Text] [PDF]  

Hemostasis and Thrombosis:

Charles Thuerlemann, André Haeberli, and Lorenzo Alberio

Monitoring Thrombin Generation by Electrochemistry: Development of an Amperometric Biosensor Screening Test for Plasma and Whole Blood
Clin Chem 2009 55: 505-512. Published online January 15, 2009; 10.1373/clinchem.2008.111963 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Denis Roche, Alexandra Mesner, Malik Al Nakib, Frederic Leonard, and Philippe Beaune

Automated Determination of Serum 1-Antitrypsin by Antitryptic Activity Measurement
Clin Chem 2009 55: 513-518. Published online January 23, 2009; 10.1373/clinchem.2008.117002 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Mark M. Kushnir, Tord Naessen, Dmitrijus Kirilovas, Andrey Chaika, Jelena Nosenko, Iryna Mogilevkina, Alan L. Rockwood, Kjell Carlström, and Jonas Bergquist

Steroid Profiles in Ovarian Follicular Fluid from Regularly Menstruating Women and Women after Ovarian Stimulation
Clin Chem 2009 55: 519-526. Published online January 15, 2009; 10.1373/clinchem.2008.110262 [Abstract] [Full Text] [PDF] Supplemental Data  

Haoyue Zhang, Robert D. Stevens, Sarah P. Young, Richard Surwit, Anastasia Georgiades, Raymond Boston, and David S. Millington

A Convenient LC-MS Method for Assessment of Glucose Kinetics In Vivo with D-[¹³C₆]Glucose as a Tracer
Clin Chem 2009 55: 527-532. Published online January 30, 2009; 10.1373/clinchem.2008.113654 [Abstract] [Full Text] [PDF]  

Evidence-based Medicine and Test Utilization:

Geoffrey S. Baird, Petrie M. Rainey, Mark Wener, and Wayne Chandler

Reducing Routine Ionized Calcium Measurement
Clin Chem 2009 55: 533-540. Published online January 23, 2009; 10.1373/clinchem.2008.116707 [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Sabata Martino, Roberto Tiribuzi, Andrea Tortori, Daniele Conti, Ilaria Visigalli, Annalisa Lattanzi, Alessandra Biffi, Angela Gritti, and Aldo Orlacchio

Specific Determination of β-Galactocerebrosidase Activity via Competitive Inhibition of β-Galactosidase
Clin Chem 2009 55: 541-548. Published online January 15, 2009; 10.1373/clinchem.2008.115873 [Abstract] [Full Text] [PDF]  

Christa M. Cobbaert, Henk Baadenhuijsen, and Cas W. Weykamp

Prime Time for Enzymatic Creatinine Methods in Pediatrics
Clin Chem 2009 55: 549-558. Published online January 23, 2009; 10.1373/clinchem.2008.116863 [Abstract] [Full Text] [PDF] Supplemental Data  

Molecular Diagnostics and Genetics:

Eiji Sunami, Masaru Shinozaki, Celestia S. Higano, Robert Wollman, Tanya B. Dorff, Steven J. Tucker, Steve R. Martinez, Frederick R. Singer, and Dave S.B. Hoon

Multimarker Circulating DNA Assay for Assessing Blood of Prostate Cancer Patients
Clin Chem 2009 55: 559-567. Published online January 8, 2009; 10.1373/clinchem.2008.108498 [Abstract] [Full Text] [PDF] Supplemental Data  

Brief Communications:

Dan Liu, Tibor Schuster, Marcus Baumann, Marcel Roos, Daniel Sollinger, Jens Lutz, Uwe Heemann, and Maximilian von Eynatten

Comparison of Immunoassays for the Selective Measurement of Human High–Molecular Weight Adiponectin
Clin Chem 2009 55: 568-572. Published online January 23, 2009; 10.1373/clinchem.2008.112425 [Abstract] [Full Text] [PDF]  

Peter A. Kavsak, Andrew R. MacRae, Marie-Jeanne Yerna, and Allan S. Jaffe

Analytic and Clinical Utility of a Next-Generation, Highly Sensitive Cardiac Troponin I Assay for Early Detection of Myocardial Injury
Clin Chem 2009 55: 573-577. Published online January 23, 2009; 10.1373/clinchem.2008.116020 [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Case Study:

Stacey A. Simons, Alejandro R. Molinelli, Kimia Sobhani, Petrie M. Rainey, and Andrew N. Hoofnagle

Two Cases with Unusual Vancomycin Measurements
Clin Chem 2009 55: 578-580. [Extract] [Full Text] [PDF]  

David F. Keren

Commentary
Clin Chem 2009 55: 580-581. [Extract] [Full Text] [PDF]  

Amitava Dasgupta

Commentary
Clin Chem 2009 55: 581-582. [Extract] [Full Text] [PDF]  

Citation Classic:

Basil T. Doumas and Theodore Peters, Jr.

Origins of Dye-Binding Methods for Measuring Serum Albumin
Clin Chem 2009 55: 583-584. [Extract] [Full Text] [PDF]  

Inspiring Minds:

Misia Landau

Carl Burtis
Clin Chem 2009 55: 585-586. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Siew Lee Fong, Ji Tuan Zhang, Che Kang Lim, Kong Weng Eu, and Yanqun Liu

Comparison of 7 Methods for Extracting Cell-Free DNA from Serum Samples of Colorectal Cancer Patients
Clin Chem 2009 55: 587-589. [Extract] [Full Text] [PDF]  

Stephanie J. Marin, Christine Moore, and Gwendolyn A. McMillin

Cross-Reactivity of Phentermine with an Immunoassay Designed to Detect Amphetamine in a Meconium Specimen
Clin Chem 2009 55: 589-590. [Extract] [Full Text] [PDF]  

Evangelos Giannitsis, Heinz Juergen Roth, Renate M. Leithäuser, Juergen Scherhag, Ralt Beneke, and Hugo A. Katus

New Highly Sensitivity Assay Used to Measure Cardiac Troponin T Concentration Changes During a Continuous 216-km Marathon
Clin Chem 2009 55: 590-592. [Extract] [Full Text] [PDF]  

Metha Apiwattanakul, Andrew McKeon, James P. Fryer, Shannon R. Hinson, Sean J. Pittock, and Vanda A. Lennon

AQP4-IgG Immunoprecipitation Assay Optimization
Clin Chem 2009 55: 592-594. [Extract] [Full Text] [PDF]  

Charles M. Quick, Angela Klipp, Gail L. Woods, John W. Theus, and Joshua A. Bornhorst

Comparison of Bromcresol Purple and Capillary Protein Electrophoresis for Quantification of Serum Albumin in Multiple Myeloma
Clin Chem 2009 55: 594-596. [Extract] [Full Text] [PDF]  

Victor R. De Jesus, Hui Zhou, Robert F. Vogt, and W. Harry Hannon

Changes in Solvent Composition in Tandem Mass Spectrometry Multiplex Assay for Lysosomal Storage Disorders Do Not Affect Assay Results
Clin Chem 2009 55: 596-598. [Extract] [Full Text] [PDF]  

Clinical Chemist:

Lily Robinson and the Mount Vernon Affair
Clin Chem 2009 55: 599-600. [Extract] [Full Text] [PDF]  

Clinical Chemistry Podcasts
Clin Chem 2009 55: 600. [Extract] [Full Text] [PDF]  

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