Editorials:

Ann M. Gronowski and David G. Grenache

Characterization of the hCG Variants Recognized by Different hCG Immunoassays: An Important Step Toward Standardization of hCG Measurements
Clin Chem 2009 55: 1447-1449. Published online June 18, 2009; 10.1373/clinchem.2009.129205 [Extract] [Full Text] [PDF]  

Perspectives:

Yuling Hong

Burden of Cardiovascular Disease in Asia: Big Challenges and Ample Opportunities for Action and Making a Difference
Clin Chem 2009 55: 1450-1452. Published online June 4, 2009; 10.1373/clinchem.2009.125369 [Extract] [Full Text] [PDF]  

Michaela J. Higgins and Vered Stearns

Understanding Resistance to Tamoxifen in Hormone Receptor–Positive Breast Cancer
Clin Chem 2009 55: 1453-1455. Published online June 18, 2009; 10.1373/clinchem.2009.125377 [Extract] [Full Text] [PDF]  

Special Reports:

Larry D. Bowers

The International Antidoping System and Why It Works
Clin Chem 2009 55: 1456-1461. Published online June 25, 2009; 10.1373/clinchem.2009.127837 [Extract] [Full Text] [PDF]  

Mini-Review:

Roger K. Schindhelm, Leonard P. van der Zwan, Tom Teerlink, and Peter G. Scheffer

Myeloperoxidase: A Useful Biomarker for Cardiovascular Disease Risk Stratification?
Clin Chem 2009 55: 1462-1470. Published online June 25, 2009; 10.1373/clinchem.2009.126029 [Abstract] [Full Text] [PDF]  

Review:

Lasse Sommer Kristensen and Lise Lotte Hansen

PCR-Based Methods for Detecting Single-Locus DNA Methylation Biomarkers in Cancer Diagnostics, Prognostics, and Response to Treatment
Clin Chem 2009 55: 1471-1483. Published online June 11, 2009; 10.1373/clinchem.2008.121962 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Catharine M. Sturgeon, Peter Berger, Jean-Michel Bidart, Steven Birken, Chris Burns, Robert J. Norman, Ulf-Håkan Stenman on behalf of the IFCC Working Group on hCG

Differences in Recognition of the 1st WHO International Reference Reagents for hCG-Related Isoforms by Diagnostic Immunoassays for Human Chorionic Gonadotropin
Clin Chem 2009 55: 1484-1491. Published online June 18, 2009; 10.1373/clinchem.2009.124578 [Abstract] [Full Text] [PDF] Supplemental Data  

Automation and Analytical Techniques:

Jens Dreier, Tanja Vollmer, and Knut Kleesiek

Novel Flow Cytometry–Based Screening for Bacterial Contamination of Donor Platelet Preparations Compared with Other Rapid Screening Methods
Clin Chem 2009 55: 1492-1502. Published online June 4, 2009; 10.1373/clinchem.2008.122515 [Abstract] [Full Text] [PDF]  

Ju Luan, Jing Yuan, Xiaohe Li, Shengnan Jin, Ling Yu, Mingfeng Liao, Hongmei Zhang, Cheng Xu, Qing He, Bin Wen, Xunhua Zhong, Xinchun Chen, Henry L.Y. Chan, Joseph J.Y. Sung, Boping Zhou, and Chunming Ding

Multiplex Detection of 60 Hepatitis B Virus Variants by MALDI-TOF Mass Spectrometry
Clin Chem 2009 55: 1503-1509. Published online June 18, 2009; 10.1373/clinchem.2009.124859 [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Immunology:

Manuela M. Giarin, Luisa Giaccone, Roberto Sorasio, Christian Sfiligoi, Barbara Amoroso, Federica Cavallo, Alessia Cipriani, Antonio Palumbo, and Mario Boccadoro

Serum Free Light Chain Ratio, Total / Ratio, and Immunofixation Results Are Not Prognostic Factors after Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma
Clin Chem 2009 55: 1510-1516. Published online June 11, 2009; 10.1373/clinchem.2009.124370 [Abstract] [Full Text] [PDF]  

Jerry A. Katzmann, Robert A. Kyle, Joanne Benson, Dirk R. Larson, Melissa R. Snyder, John A. Lust, S. Vincent Rajkumar, and Angela Dispenzieri

Screening Panels for Detection of Monoclonal Gammopathies
Clin Chem 2009 55: 1517-1522. Published online June 11, 2009; 10.1373/clinchem.2009.126664 [Abstract] [Full Text] [PDF]  

David L. Murray, Euijung Ryu, Melissa R. Snyder, and Jerry A. Katzmann

Quantitation of Serum Monoclonal Proteins: Relationship between Agarose Gel Electrophoresis and Immunonephelometry
Clin Chem 2009 55: 1523-1529. Published online June 11, 2009; 10.1373/clinchem.2009.124461 [Abstract] [Full Text] [PDF]  

Point-of-Care Testing:

Pierre N. Floriano, Nicolaos Christodoulides, Craig S. Miller, Jeffrey L. Ebersole, John Spertus, Beate G. Rose, Denis F. Kinane, M. John Novak, Steven Steinhubl, Shelley Acosta, Sanghamitra Mohanty, Priya Dharshan, Chih-ko Yeh, Spencer Redding, Wieslaw Furmaga, and John T. McDevitt

Use of Saliva-Based Nano-Biochip Tests for Acute Myocardial Infarction at the Point of Care: A Feasibility Study
Clin Chem 2009 55: 1530-1538. Published online June 25, 2009; 10.1373/clinchem.2008.117713 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Edzard Schwedhelm, Vanessa Xanthakis, Renke Maas, Lisa M. Sullivan, Friedrich Schulze, Ulrich Riederer, Ralf A. Benndorf, Rainer H. Böger, and Ramachandran S. Vasan

Asymmetric Dimethylarginine Reference Intervals Determined with Liquid Chromatography–Tandem Mass Spectrometry: Results from the Framingham Offspring Cohort
Clin Chem 2009 55: 1539-1545. Published online June 18, 2009; 10.1373/clinchem.2009.124263 [Abstract] [Full Text] [PDF] Supplemental Data  

Molecular Diagnostics and Genetics:

Naoya Hosono, Mamoru Kato, Kazuma Kiyotani, Taisei Mushiroda, Sadaaki Takata, Hiroko Sato, Hanae Amitani, Yumiko Tsuchiya, Keiko Yamazaki, Tatsuhiko Tsunoda, Hitoshi Zembutsu, Yusuke Nakamura, and Michiaki Kubo

CYP2D6 Genotyping for Functional-Gene Dosage Analysis by Allele Copy Number Detection
Clin Chem 2009 55: 1546-1554. Published online June 18, 2009; 10.1373/clinchem.2009.123620 [Abstract] [Full Text] [PDF] Supplemental Data  

Brief Communications:

Leo L.M. Poon, K.H. Chan, G.J. Smith, C.S.W. Leung, Y. Guan, K.Y. Yuen, and J.S.M. Peiris

Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays
Clin Chem 2009 55: 1555-1558. Published online May 13, 2009; 10.1373/clinchem.2009.130229 [Abstract] [Full Text] [PDF]  

Christoph Ausch, Young-Ho Kim, Karen D. Tsuchiya, Slavomir Dzieciatkowski, Mary K. Washington, Christos Paraskeva, Jerry Radich, and William M. Grady

Comparative Analysis of PCR-Based Biomarker Assay Methods for Colorectal Polyp Detection from Fecal DNA
Clin Chem 2009 55: 1559-1563. Published online June 18, 2009; 10.1373/clinchem.2008.122937 [Abstract] [Full Text] [PDF] Supplemental Data  

Niels Tørring

Performance of First-Trimester Screening between Gestational Weeks 7 and 13
Clin Chem 2009 55: 1564-1567. Published online June 18, 2009; 10.1373/clinchem.2009.125922 [Abstract] [Full Text] [PDF]  

Suk-Hang Cheng, Patrick Kwan, Ho-Keung Ng, and Margaret H.-L. Ng

New Testing Approach in HLA Genotyping Helps Overcome Barriers in Effective Clinical Practice
Clin Chem 2009 55: 1568-1572. Published online June 25, 2009; 10.1373/clinchem.2009.127894 [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Case Study:

Smita Krishnamurthy, Kevin M. Korenblat, and Mitchell G. Scott

Persistent Increase in Aspartate Aminotransferase in an Asymptomatic Patient
Clin Chem 2009 55: 1573-1575. [Extract] [Full Text] [PDF]  

D. Robert Dufour

Commentary
Clin Chem 2009 55: 1576. [Extract] [Full Text] [PDF]  

Henry C. Bodenheimer

Commentary
Clin Chem 2009 55: 1576-1577. [Extract] [Full Text] [PDF]  

Citation Classic:

Charles B. Nemeroff and Michael J. Owens

The Role of Serotonin in the Pathophysiology of Depression: As Important As Ever
Clin Chem 2009 55: 1578-1579. Published online June 4, 2009; 10.1373/clinchem.2009.123752 [Extract] [Full Text] [PDF]  

Q&A:

David B. Sacks

Tight Glucose Control in Critically Ill Patients: Should Glucose Meters Be Used?
Clin Chem 2009 55: 1580-1583. Published online June 25, 2009; 10.1373/clinchem.2009.131318 [Extract] [Full Text] [PDF]  

Letters to the Editor:

Jos P. M. Wielders and Ferdinand A. Wijnberg

Preanalytical Stability of 25(OH)–Vitamin D₃ in Human Blood or Serum at Room Temperature: Solid as a Rock
Clin Chem 2009 55: 1584-1585. Published online June 18, 2009; 10.1373/clinchem.2008.117366 [Extract] [Full Text] [PDF]  

Andries J. Bakker, Ageeth Bierma-Ram, Coby Elderman-van der Werf, Marcia L. Strijdhaftig, and Jelmer J. van Zanden

Quantitation of Serum Free Light Chains
Clin Chem 2009 55: 1585-1587. Published online June 4, 2009; 10.1373/clinchem.2008.122416 [Extract] [Full Text] [PDF]  

Armin P. Piehler and Petter Urdal

In Reply
Clin Chem 2009 55: 1587-1588. Published online June 11, 2009; 10.1373/clinchem.2009.126821 [Extract] [Full Text] [PDF]  

Nadhipuram V. Bhagavan, Ji-Sook Ha, Joo-Ho Park, Stacey A. Honda, Carlos N. Rios, Cheryl Sugiyama, Gale K. Fujitani, Irene K. Takeuchi, and Chung-Eun Ha

Utility of Serum Fatty Acid Concentrations as a Marker for Acute Myocardial Infarction and Their Potential Role in the Formation of Ischemia-Modified Albumin: A Pilot Study
Clin Chem 2009 55: 1588-1590. Published online June 4, 2009; 10.1373/clinchem.2008.123315 [Extract] [Full Text] [PDF]  

Timothy K. Amukele, Andrew N. Hoofnagle, and Michael L. Astion

Use of a Resident On-Call Database to Characterize Failures in Communicating Critical Laboratory Results
Clin Chem 2009 55: 1590-1591. Published online June 4, 2009; 10.1373/clinchem.2009.125385 [Extract] [Full Text] [PDF]  

Maciej Adamczyk, R. Jeffrey Brashear, and Phillip G. Mattingly

Prevalence of Autoantibodies to Cardiac Troponin T in Healthy Blood Donors
Clin Chem 2009 55: 1592-1593. Published online June 4, 2009; 10.1373/clinchem.2009.125781 [Extract] [Full Text] [PDF]  

J. Gustav Smith, Christopher Newton-Cheh, Bo Hedblad, Joachim Struck, Nils G. Morgenthaler, Andreas Bergmann, Thomas J. Wang, and Olle Melander

Distribution and Correlates of Midregional Proadrenomedullin in the General Population
Clin Chem 2009 55: 1593-1595. Published online June 18, 2009; 10.1373/clinchem.2009.126482 [Extract] [Full Text] [PDF]  

Book, Software and Website Reviews:

Alan T. Remaley

Website Review Directus. Jacksonville, Florida: Informed CME Learning. https://www.pdh.cme.edu/.
Clin Chem 2009 55: 1596-1597. [Extract] [Full Text] [PDF]  

Clinical Chemist:

Lily Robinson and Conventional Wisdom
Clin Chem 2009 55: 1598-1599. [Extract] [Full Text] [PDF]  

Adriana Rivero, Roberto Muñoz, and María Moreno

What Is Your Guess?
Clin Chem 2009 55: 1600. [Extract] [Full Text] [PDF]  

Unveiling the Right Side
Clin Chem 2009 55: 1601. [Extract] [Full Text] [PDF]  

Corrections:

Correction
Clin Chem 2009 55: 1602. [Extract] [Full Text] [PDF] Supplemental Data  

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