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Submitting a Reply

Usually a Reply is requested by the editor and pertains to a specific manuscript. Often it is a manufacturer's response.

A Reply is generally no more than 750 words, excluding the words in the reference list.

On the first submission page, there are two things you'll need to do to indicate your manuscript is a reply to this paper:

1. Choose "Reply" as the article type, and
2. Check both boxes next to the "Companion Papers" heading, being sure to include the Clinical Chemistry manuscript ID number sent to you as the manuscript to which your reply should be linked.

Aside from these requirements, your Reply can be submitted as a normal manuscript:

Fill in the rest of the page of manuscript metadata. Items highlighted in red are mandatory but the more information, the better. Click Save/Continue.

Fill in the next page of author metadata. Click Save/Continue.

Enter the number of image files you need to upload (if any). The manuscript has already been designated as one file. It is rare for a Reply to include an image or a table.

For Images: Only .eps and .tif image formats, resolution 600 dpi, are acceptable. You may use PowerPoint (.ppt) files if the fonts are embedded and there is only one image per slide, one slide per file. You will need to upload your manuscript as a Word document. Please do not upload PDF files.

Click Save/Continue.

The system will then offer a browse button for the manuscript and image. Click each browse button and find the corresponding file on your computer, each in turn. When completed, click upload.

At this point the system will ask you to close your browser and wait for an email acknowledgement that your manuscript and image have been converted into a PDF for review purposes. When the email comes to the email account you registered with, you will be asked to return to your author center and approve all parts of the uploaded manuscript in ‘Manuscripts Ready for you to Proof.’

Even though you uploaded your manuscript and image separately, your system-generated PDF file should include all parts of your manuscript: your title page, your manuscript body, references (and any table or figure deemed necessary). The abstract (first full page of text) and cover letter should appear in the first page Manuscript Metadata windows.

Please edit or approve until all boxes are filled. Click Approve.

You are finished and will receive a confirmation email that your manuscript has been received in the Clinical Chemistry office.